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    South America
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  • Adults (25+)
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385 Cruises

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  • 5-Night South America Cruise

    5-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Fri, Dec 6, 2019
    Returns: Wed, Dec 11, 2019
    Depart – Rio de Janeiro, Brazil
    • IlhaBela, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    Returns – Buenos Aires, Argentina
    Rio de Janeiro, Brazil - IlhaBela, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina
    from
    C$1311*
    *restrictions apply
    Taxes of C$94 Included


  • 4-Night South America Cruise

    4-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Fri, Dec 13, 2019
    Returns: Tue, Dec 17, 2019
    Depart – Santos, Brazil
    • Itajai, Brazil
    • At Sea
    • Montevideo, Uruguay
    Returns – Buenos Aires, Argentina
    Santos, Brazil - Itajai, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina
    from
    C$604*
    *restrictions apply
    Taxes of C$75 Included
  • 3-Night South America Cruise

    3-Night South America Cruise
    MSC Cruises
    MSC Seaview
    Depart: Mon, Mar 16, 2020
    Returns: Thu, Mar 19, 2020
    Depart – Santos, Brazil
    • Balneario Camboriu, Brazil
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - Balneario Camboriu, Brazil - At Sea - Santos, Brazil
    from
    C$697*
    *restrictions apply
    Taxes of C$56 Included
  • 6-Night South America Cruise

    6-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Feb 9, 2020
    Returns: Sat, Feb 15, 2020
    Depart – Rio de Janeiro, Brazil
    • Buzios, Brazil
    • At Sea
    • Salvador, Brazil
    • Ilheus, Brazil
    • At Sea
    Returns – Rio de Janeiro, Brazil
    Rio de Janeiro, Brazil - Buzios, Brazil - At Sea - Salvador, Brazil - Ilheus, Brazil - At Sea - Rio de Janeiro, Brazil
    from
    C$927*
    *restrictions apply
    Taxes of C$112 Included
  • 6-Night South America Cruise

    6-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sat, Feb 29, 2020
    Returns: Fri, Mar 6, 2020
    Depart – Rio de Janeiro, Brazil
    • At Sea
    • Ilheus, Brazil
    • Salvador, Brazil
    • At Sea
    • Buzios, Brazil
    Returns – Rio de Janeiro, Brazil
    Rio de Janeiro, Brazil - At Sea - Ilheus, Brazil - Salvador, Brazil - At Sea - Buzios, Brazil - Rio de Janeiro, Brazil
    from
    C$881*
    *restrictions apply
    Taxes of C$112 Included
  • 9-Night South America Cruise

    9-Night South America Cruise
    MSC Cruises
    MSC Musica
    Depart: Sat, Feb 1, 2020
    Returns: Mon, Feb 10, 2020
    Depart – Buenos Aires, Argentina
    • At Sea
    • At Sea
    • Ilha Grande, Brazil
    • Buzios, Brazil
    • Rio de Janeiro, Brazil
    • IlhaBela, Brazil
    • At Sea
    • Punta del Este, Uruguay
    Returns – Buenos Aires, Argentina
    Buenos Aires, Argentina - At Sea - At Sea - Ilha Grande, Brazil - Buzios, Brazil - Rio de Janeiro, Brazil - IlhaBela, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina
    from
    C$1947*
    *restrictions apply
    Taxes of C$168 Included
  • 4-Night South America Cruise

    4-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Mon, Dec 2, 2019
    Returns: Fri, Dec 6, 2019
    Depart – Santos, Brazil
    • Rio de Janeiro, Brazil
    • At Sea
    • Ilha Grande, Brazil
    Returns – Rio de Janeiro, Brazil
    Santos, Brazil - Rio de Janeiro, Brazil - At Sea - Ilha Grande, Brazil - Rio de Janeiro, Brazil
    from
    C$622*
    *restrictions apply
    Taxes of C$75 Included
  • 4-Night South America Cruise

    4-Night South America Cruise
    MSC Cruises
    MSC Seaview
    Depart: Tue, Feb 18, 2020
    Returns: Sat, Feb 22, 2020
    Depart – Santos, Brazil
    • Balneario Camboriu, Brazil
    • Porto Belo, Brazil
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - Balneario Camboriu, Brazil - Porto Belo, Brazil - At Sea - Santos, Brazil
    from
    C$837*
    *restrictions apply
    Taxes of C$75 Included
  • 14-Night South America Cruise

    BEST
    VALUE*
    14-Night South America Cruise
    Norwegian Cruise Line
    Norwegian Star
    Depart: Sat, Dec 21, 2019
    Returns: Sat, Jan 4, 2020
    Depart – San Antonio, Chile
    • At Sea
    • Puerto Montt, Chile
    • Puerto Chacabuco, Chile
    • Chilean Fjords, Chile
    • At Sea
    • Strait of Magellan, Chile
    • Punta Arenas, Chile
    • Beagle Channel (Argentina/Chile)
    • Ushuaia, Argentina
    • Cape Horn, Chile
    • Port Stanley, Falkland Islands (Malvinas)
    • At Sea
    • Puerto Madryn, Argentina
    • At Sea
    • Montevideo, Uruguay
    Returns – Buenos Aires, Argentina
    San Antonio, Chile - At Sea - Puerto Montt, Chile - Puerto Chacabuco, Chile - Chilean Fjords, Chile - At Sea - Strait of Magellan, Chile - Punta Arenas, Chile - Beagle Channel (Argentina/Chile) - Ushuaia, Argentina - Cape Horn, Chile - Port Stanley, Falkland Islands (Malvinas) - At Sea - Puerto Madryn, Argentina - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 6/18
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 6/18
    • FREE WiFi & Excursion Credit - Ends 6/18
    • show more 
    from
    C$2833*
    *restrictions apply
    Taxes of C$491 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Sat, Dec 21, 2019
    Returns: Sat, Dec 28, 2019
    Depart – Itajai, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • At Sea
    • At Sea
    • Santos, Brazil
    Returns – Itajai, Brazil
    Itajai, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - At Sea - At Sea - Santos, Brazil - Itajai, Brazil
    from
    C$1080*
    *restrictions apply
    Taxes of C$131 Included

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in CAD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.